Mus musculus Gene: Kcne3
Summary
InnateDB Gene IDBG-201057.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcne3
Gene Name potassium voltage-gated channel, Isk-related subfamily, gene 3
Synonyms 2210017H05Rik; MiRP2
Species Mus musculus
Ensembl Gene ENSMUSG00000035165
Encoded Proteins
potassium voltage-gated channel, Isk-related subfamily, gene 3
potassium voltage-gated channel, Isk-related subfamily, gene 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175538:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:100176670-100184869
Strand Forward strand
Band E2
Transcripts
ENSMUST00000049333 ENSMUSP00000039353
ENSMUST00000170954 ENSMUSP00000130019
ENSMUST00000178946 ENSMUSP00000136616
ENSMUST00000179842 ENSMUSP00000136415
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005249 voltage-gated potassium channel activity
GO:0005267 potassium channel activity
GO:0015459 potassium channel regulator activity
Biological Process
GO:0006811 ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0043266 regulation of potassium ion transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Protein digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt Q9WTW2
TrEMBL Q545H9
UniProt Splice Variant
Entrez Gene 57442
UniGene Mm.282386
RefSeq NM_001190871 NM_020574 NM_001190869 NM_001190870 NM_001190950
OMIM
CCDS CCDS21495
HPRD
IMGT
MGI ID MGI:1891124
MGI Symbol Kcne3
EMBL AF076532 AK008744 AK132773 BC004629 CH466531 DQ832280
GenPept AAD28090 AAH04629 ABI30214 BAB25871 BAE21350 EDL16424 EDL16425 EDL16426 EDL16427
RNA Seq Atlas 57442