Mus musculus Gene: Srsf11
Summary
InnateDB Gene IDBG-201190.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Srsf11
Gene Name serine/arginine-rich splicing factor 11
Synonyms 0610009J05Rik; 2610019N13Rik; BF642805; Sfrs11
Species Mus musculus
Ensembl Gene ENSMUSG00000055436
Encoded Proteins
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:158010473-158036639
Strand Reverse strand
Band H4
Transcripts
ENSMUST00000069025 ENSMUSP00000063916
ENSMUST00000072875 ENSMUSP00000072651
ENSMUST00000089922
ENSMUST00000121326 ENSMUSP00000113685
ENSMUST00000152274 ENSMUSP00000127239
ENSMUST00000127778 ENSMUSP00000118652
ENSMUST00000145267
ENSMUST00000156303
ENSMUST00000126377
ENSMUST00000137444 ENSMUSP00000122686
ENSMUST00000126716 ENSMUSP00000114370
ENSMUST00000140491 ENSMUSP00000118767
ENSMUST00000147304 ENSMUSP00000115487
ENSMUST00000133090
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
TSLP pathway
REACTOME
mRNA 3'-end processing pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.223946 Mm.366429 Mm.404091
RefSeq NM_001093752 NM_001093753 NM_026989 XM_006502015 XM_006502016 XM_006502017 XM_006502018 XM_006502019 XM_006502020 XM_006502021
OMIM
CCDS CCDS17934 CCDS51102 CCDS51103
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas