Version 5.4
Mus musculus Gene: Plxnb1
Summary
InnateDB Gene IDBG-201210.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plxnb1
Gene Name plexin B1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053646
Encoded Proteins
IDBP-201212
plexin B1
IDBP-531912
plexin B1
IDBP-537737
plexin B1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164050:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:109095436-109119911
Strand Forward strand
Band F2
Transcripts
ENSMUST00000072093 ENSMUSP00000071966
ENSMUST00000131462 ENSMUSP00000115265
ENSMUST00000130366 ENSMUSP00000114358
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0017154 semaphorin receptor activity
GO:0032794 GTPase activating protein binding
Biological Process
GO:0007162 negative regulation of cell adhesion
GO:0007165 signal transduction
GO:0007275 multicellular organismal development
GO:0008360 regulation of cell shape
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0032321 positive regulation of Rho GTPase activity
GO:0033689 negative regulation of osteoblast proliferation
GO:0043931 ossification involved in bone maturation
GO:0048812 neuron projection morphogenesis
GO:0050772 positive regulation of axonogenesis
GO:0051493 regulation of cytoskeleton organization
GO:0071526 semaphorin-plexin signaling pathway
GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
Cellular Component
GO:0002116 semaphorin receptor complex
GO:0005622 intracellular
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164050
View Gene Order
ENSBTAG00000013407
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_246650
Sema4D induced cell migration and growth-cone collapse pathway
REACT_204733
G alpha (12/13) signalling events pathway
REACT_261444
Axon guidance pathway
REACT_234744
Sema4D in semaphorin signaling pathway
REACT_188576
Developmental Biology pathway
REACT_263034
Semaphorin interactions pathway
REACT_239484
Sema4D mediated inhibition of cell attachment and migration pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18407
G alpha (12/13) signalling events pathway
REACT_19266
Sema4D mediated inhibition of cell attachment and migration pathway
REACT_19277
Sema4D induced cell migration and growth-cone collapse pathway
REACT_19259
Sema4D in semaphorin signaling pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_14797
Signaling by GPCR pathway
REACT_18266
Axon guidance pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.405073 Mm.53862
RefSeq NM_172775 XM_006512075 XM_006512076 XM_006512077 XM_006512078 XM_006512079 XM_006512080 XM_006512081
OMIM
CCDS CCDS23546
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca