InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: HS3ST2

Summary

InnateDB Gene

IDBG-20138.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HS3ST2

Gene Name

heparan sulfate (glucosamine) 3-O-sulfotransferase 2

Synonyms

30ST2; 3OST2

Species

Homo sapiens

Ensembl Gene

ENSG00000122254

Encoded Proteins

IDBP-20140

heparan sulfate (glucosamine) 3-O-sulfotransferase 2

IDBP-753021

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. This gene is expressed predominantly in brain and may play a role in the nervous system. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:22814177-22916338

Strand

Forward strand

Band

p12.2

Transcripts

ENST00000261374	ENSP00000261374
ENST00000473392	ENSP00000454505

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	0
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008146	sulfotransferase activity
GO:0033871	[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006024	glycosaminoglycan biosynthetic process
GO:0007623	circadian rhythm
GO:0008152	metabolic process
GO:0030203	glycosaminoglycan metabolic process
GO:0044281	small molecule metabolic process