Version 5.4
Homo sapiens Gene: HIC2
Summary
InnateDB Gene IDBG-2014.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HIC2
Gene Name hypermethylated in cancer 2
Synonyms HRG22; ZBTB30; ZNF907
Species Homo sapiens
Ensembl Gene ENSG00000169635
Encoded Proteins
IDBP-292673
hypermethylated in cancer 2
IDBP-292674
hypermethylated in cancer 2
IDBP-364869
hypermethylated in cancer 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:21417404-21451463
Strand Forward strand
Band q11.21
Transcripts
ENST00000407464 ENSP00000385319
ENST00000407598 ENSP00000384889
ENST00000443632 ENSP00000387757
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000050240
View Gene Order
ENSBTAG00000005951
Not yet available
Cross-References
SwissProt Q96JB3
TrEMBL
UniProt Splice Variant
Entrez Gene 23119
UniGene Hs.632767
RefSeq XM_005261395 NM_015094
HUGO HGNC:18595
OMIM 607712
CCDS CCDS13789
HPRD 07412
IMGT
EMBL AB028943 AF349035 AJ313204 AL162003 AP000557 BC094787 CR456377
GenPept AAH94787 AAK72951 BAA82972 CAB82344 CAC70715 CAG30263
RNA Seq Atlas 23119

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca