Version 5.4
Mus musculus Gene: Mfap2
Summary
InnateDB Gene IDBG-201581.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mfap2
Gene Name microfibrillar-associated protein 2
Synonyms AI893631; Magp; Magp1
Species Mus musculus
Ensembl Gene ENSMUSG00000060572
Encoded Proteins
IDBP-201587
microfibrillar-associated protein 2
IDBP-626561
microfibrillar-associated protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117122:
Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:141010418-141015984
Strand Forward strand
Band D3
Transcripts
ENSMUST00000071977 ENSMUSP00000071868
ENSMUST00000124506
ENSMUST00000166376 ENSMUSP00000132711
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001968 fibronectin binding
GO:0005515 protein binding
GO:0070051 fibrinogen binding
Biological Process
GO:0030220 platelet formation
Cellular Component
GO:0001527 microfibril
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000117122
View Gene Order
ENSBTAG00000003832
Not yet available
Pathways
NETPATH
REACTOME
REACT_198996
Elastic fibre formation pathway
REACT_198998
Molecules associated with elastic fibres pathway
REACT_206066
Extracellular matrix organization pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150331
Molecules associated with elastic fibres pathway
REACT_150366
Elastic fibre formation pathway
REACT_118779
Extracellular matrix organization pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P55002
TrEMBL Q99PM0
UniProt Splice Variant
Entrez Gene 17150
UniGene
RefSeq NM_008546 XM_006538612 NM_001161799
OMIM
CCDS CCDS18860
HPRD
IMGT
MGI ID MGI:99559
MGI Symbol Mfap2
EMBL AF268473 AK160213 AK164920 AL645625 BC035490 L23769
GenPept AAA16448 AAG49554 AAH35490 BAE35693 BAE37967
RNA Seq Atlas 17150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca