Mus musculus Gene: Pigc
Summary
InnateDB Gene IDBG-201686.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigc
Gene Name phosphatidylinositol glycan anchor biosynthesis, class C
Synonyms 3110030E07Rik; AW212108
Species Mus musculus
Ensembl Gene ENSMUSG00000026698
Encoded Proteins
phosphatidylinositol glycan anchor biosynthesis, class C
phosphatidylinositol glycan anchor biosynthesis, class C
phosphatidylinositol glycan anchor biosynthesis, class C
phosphatidylinositol glycan anchor biosynthesis, class C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135845:
This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:161969186-162027106
Strand Forward strand
Band H2.1
Transcripts
ENSMUST00000028021 ENSMUSP00000028021
ENSMUST00000111594 ENSMUSP00000107221
ENSMUST00000161826
ENSMUST00000160881 ENSMUSP00000125321
ENSMUST00000159648 ENSMUSP00000125562
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of glycosylphosphatidylinositol (GPI) pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.400139 Mm.402432 Mm.45106
RefSeq NM_001039045 NM_026078 XM_006496959
OMIM
CCDS CCDS15419
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas