Bos taurus Gene: PIGC
Summary
InnateDB Gene IDBG-632247.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIGC
Gene Name Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000024542
Encoded Proteins
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135845:
This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:40785953-40788409
Strand Reverse strand
Band
Transcripts
ENSBTAT00000034135 ENSBTAP00000034036
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of glycosylphosphatidylinositol (GPI) pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q3ZBX1
TrEMBL
UniProt Splice Variant
Entrez Gene 510483
UniGene Bt.49348
RefSeq NM_001034383 XM_005216899
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103058
GenPept AAI03059
RNA Seq Atlas 510483