Version 5.4
Mus musculus Gene: Arhgef17
Summary
InnateDB Gene IDBG-201713.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgef17
Gene Name Rho guanine nucleotide exchange factor (GEF) 17
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032875
Encoded Proteins
IDBP-267533
Rho guanine nucleotide exchange factor (GEF) 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110237:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:100869746-100932161
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000107032 ENSMUSP00000102647
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0030036 actin cytoskeleton organization
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0015629 actin cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110237
View Gene Order
ENSBTAG00000012505
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_209641
NRAGE signals death through JNK pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_204413
Cell death signalling via NRAGE, NRIF and NADE pathway
REACT_204733
G alpha (12/13) signalling events pathway
REACT_210090
Rho GTPase cycle pathway
REACT_248921
Signalling by NGF pathway
REACT_188257
Signal Transduction pathway
REACT_210847
p75 NTR receptor-mediated signalling pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_13638
NRAGE signals death through JNK pathway
REACT_18407
G alpha (12/13) signalling events pathway
REACT_11051
Rho GTPase cycle pathway
REACT_11061
Signalling by NGF pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_14797
Signaling by GPCR pathway
REACT_13776
p75 NTR receptor-mediated signalling pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_13720
Cell death signalling via NRAGE, NRIF and NADE pathway
KEGG
INOH
PID NCI
rhoa_reg_pathway
Regulation of RhoA activity
Cross-References
SwissProt Q80U35
TrEMBL
UniProt Splice Variant
Entrez Gene 207212
UniGene Mm.29954
RefSeq NM_001081116
OMIM
CCDS CCDS40040
HPRD
IMGT
MGI ID MGI:2673002
MGI Symbol Arhgef17
EMBL AC116586 AC150744 AK033211 AK122250
GenPept BAC28199 BAC65532
RNA Seq Atlas 207212

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca