Version 5.4
Homo sapiens Gene: PELO
Summary
InnateDB Gene IDBG-20210.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PELO
Gene Name pelota homolog (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000152684
Encoded Proteins
IDBP-20214
pelota homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:52787940-52804046
Strand Forward strand
Band q11.2
Transcripts
ENST00000274311 ENSP00000274311
ENST00000506949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 26 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0007049 cell cycle
GO:0008283 cell proliferation
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay
GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay
GO:0071025 RNA surveillance
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042275
View Gene Order
ENSBTAG00000003268
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9BRX2
TrEMBL
UniProt Splice Variant
Entrez Gene 53918
UniGene
RefSeq NM_015946
HUGO HGNC:8829
OMIM 605757
CCDS CCDS3956
HPRD
IMGT
EMBL AC026230 AF132951 AF139828 AF143952 AY117399 BC005889 BC007249 BC007650 BC022789
GenPept AAD27726 AAG22574 AAG22575 AAH05889 AAH07249 AAH07650 AAH22789 AAM89414
RNA Seq Atlas 53918

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca