Version 5.4
Mus musculus Gene: Casc4
Summary
InnateDB Gene IDBG-202524.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Casc4
Gene Name cancer susceptibility candidate 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000060227
Encoded Proteins
IDBP-202526
cancer susceptibility candidate 4
IDBP-202528
cancer susceptibility candidate 4
IDBP-202532
cancer susceptibility candidate 4
IDBP-259954
cancer susceptibility candidate 4
IDBP-536277
cancer susceptibility candidate 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166734:
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:121866970-121936220
Strand Forward strand
Band E5
Transcripts
ENSMUST00000078752 ENSMUSP00000077811
ENSMUST00000089912 ENSMUSP00000087357
ENSMUST00000089915 ENSMUSP00000087360
ENSMUST00000110586 ENSMUSP00000106216
ENSMUST00000127475
ENSMUST00000135416
ENSMUST00000126256
ENSMUST00000136023 ENSMUSP00000117883
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166734
View Gene Order
ENSBTAG00000012545
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.292109 Mm.381538 Mm.405848 Mm.472544
RefSeq NM_001205369 NM_001205370 NM_001205371 NM_177054 NM_199038
OMIM
CCDS CCDS16650 CCDS50686 CCDS57183 CCDS57184
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca