Mus musculus Gene: Kazn
Summary
InnateDB Gene IDBG-202551.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kazn
Gene Name kazrin, periplakin interacting protein
Synonyms 2310007B04Rik; 9030409G11Rik; AI256607; AI666764; AW061099; Kaz; Kazrin
Species Mus musculus
Ensembl Gene ENSMUSG00000040606
Encoded Proteins
kazrin, periplakin interacting protein
kazrin, periplakin interacting protein
kazrin, periplakin interacting protein
kazrin, periplakin interacting protein
kazrin, periplakin interacting protein
kazrin, periplakin interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189337:
This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:142102390-142239401
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000036476 ENSMUSP00000038835
ENSMUST00000155023 ENSMUSP00000116071
ENSMUST00000135922
ENSMUST00000129032 ENSMUSP00000115897
ENSMUST00000148812
ENSMUST00000144611
ENSMUST00000173068 ENSMUSP00000134498
ENSMUST00000172864 ENSMUSP00000133972
ENSMUST00000174432 ENSMUSP00000134631
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0031424 keratinization
Cellular Component
GO:0001533 cornified envelope
GO:0005737 cytoplasm
GO:0030057 desmosome
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 71529
UniGene Mm.255986 Mm.400827 Mm.422344
RefSeq NM_144531 NM_001109685
OMIM
CCDS CCDS51350
HPRD
IMGT
MGI ID MGI:1918779
MGI Symbol Kazn
EMBL
GenPept
RNA Seq Atlas 71529