Version 5.4
Mus musculus Protein: Kazn
Summary
InnateDB Protein IDBP-202555.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kazn
Protein Name kazrin, periplakin interacting protein
Synonyms 2310007B04Rik; 9030409G11Rik; AI256607; AI666764; AW061099; Kaz; Kazrin;
Species Mus musculus
Ensembl Protein ENSMUSP00000038835
InnateDB Gene IDBG-202551 (Kazn)
Protein Structure
UniProt Annotation
Function Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
Subcellular Localization Cell junction {ECO:0000269PubMed:16086310}. Nucleus {ECO:0000269PubMed:16086310}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:16086310}. Note=In an antibody regognizing isoform 2 and isoform 3 has been used. {ECO:0000269PubMed:16086310}.
Disease Associations
Tissue Specificity Expressed in skin interfollicular epidermis and hair follicles. Expressed in tongue epithelium basal suprabasal layers. {ECO:0000269PubMed:15337775}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0031424 keratinization
Cellular Component
GO:0001533 cornified envelope
GO:0005737 cytoplasm
GO:0030057 desmosome
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:1918779
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q69ZS8
PhosphoSite PhosphoSite-Q69ZS8
TrEMBL
UniProt Splice Variant
Entrez Gene 71529
UniGene Mm.422344
RefSeq NP_001103155
MGI ID
MGI Symbol Kazn
OMIM
CCDS CCDS51350
HPRD
IMGT
EMBL AK052809 AK173090 AL663037 BC022941 BX537122
GenPept AAH22941 BAC35155 BAD32368 CAM13390 CAM27950

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca