Mus musculus Gene: Prdm2
Summary
InnateDB Gene IDBG-202598.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prdm2
Gene Name PR domain containing 2, with ZNF domain
Synonyms 4833427P12Rik; E330024L24Rik; Gm1033; Gm19732; KMT8; Riz; Riz1; Znfpr1c1
Species Mus musculus
Ensembl Gene ENSMUSG00000057637
Encoded Proteins
PR domain containing 2, with ZNF domain
PR domain containing 2, with ZNF domain
PR domain containing 2, with ZNF domain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116731:
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:143107391-143212995
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000105778 ENSMUSP00000101404
ENSMUST00000154280 ENSMUSP00000117741
ENSMUST00000134791 ENSMUSP00000116458
ENSMUST00000156909
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL Q8C2W5
UniProt Splice Variant
Entrez Gene 110593
UniGene Mm.456549
RefSeq NM_001081355 NM_001256380 XM_006538485 XM_006538486 XM_006538487 XM_006538488
OMIM
CCDS CCDS38942
HPRD
IMGT
MGI ID MGI:107628
MGI Symbol Prdm2
EMBL AK087820 AL606915
GenPept BAC40014
RNA Seq Atlas 110593