Version 5.4
Mus musculus Gene: Art1
Summary
InnateDB Gene IDBG-202609.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Art1
Gene Name ADP-ribosyltransferase 1
Synonyms ADPRT; ARTC1; Yac-1
Species Mus musculus
Ensembl Gene ENSMUSG00000030996
Encoded Proteins
IDBP-202611
ADP-ribosyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129744:
ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:102101743-102111148
Strand Forward strand
Band E2
Transcripts
ENSMUST00000033300 ENSMUSP00000033300
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity
Biological Process
GO:0006471 protein ADP-ribosylation
Cellular Component
GO:0009986 cell surface
GO:0031225 anchored component of membrane
GO:0033017 sarcoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129744
View Gene Order
ENSBTAG00000006345
Not yet available
Pathways
NETPATH
REACTOME
REACT_199049
Defensins pathway
REACT_239142
Innate Immune System pathway
REACT_260145
Alpha-defensins pathway
REACT_230745
Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115574
Alpha-defensins pathway
REACT_115846
Defensins pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q60935
TrEMBL Q545U9
UniProt Splice Variant
Entrez Gene 11870
UniGene Mm.261071
RefSeq NM_009710 XM_006507254
OMIM
CCDS CCDS21526
HPRD
IMGT
MGI ID MGI:107511
MGI Symbol Art1
EMBL AJ132041 AJ132042 AJ132043 AJ132044 AK003107 AK009902 BC063760 BC132492 BC132496 CH466531 U31510 X95825 X95842
GenPept AAB18628 AAH63760 AAI32493 AAI32497 BAB22570 BAB26574 CAA65094 CAA65099 CAB38369 EDL16577 EDL16579
RNA Seq Atlas 11870

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca