Version 5.4
Mus musculus Gene: Slc30a4
Summary
InnateDB Gene IDBG-203165.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc30a4
Gene Name solute carrier family 30 (zinc transporter), member 4
Synonyms lm; znT-4; Znt4
Species Mus musculus
Ensembl Gene ENSMUSG00000005802
Encoded Proteins
IDBP-203167
solute carrier family 30 (zinc transporter), member 4
IDBP-203169
solute carrier family 30 (zinc transporter), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104154:
Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:122681233-122702663
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000005952 ENSMUSP00000005952
ENSMUST00000099457 ENSMUSP00000097056
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0006829 zinc ion transport
GO:0009636 response to toxic substance
GO:0055069 zinc ion homeostasis
GO:0055085 transmembrane transport
GO:0061088 regulation of sequestering of zinc ion
Cellular Component
GO:0005737 cytoplasm
GO:0005770 late endosome
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000104154
View Gene Order
ENSBTAG00000021019
Not yet available
Cross-References
SwissProt
TrEMBL A2AK40
UniProt Splice Variant
Entrez Gene 22785
UniGene Mm.27801 Mm.413632 Mm.448768
RefSeq NM_001290993 XM_006499170 NM_011774
OMIM
CCDS CCDS71131 CCDS16667
HPRD
IMGT
MGI ID MGI:1345282
MGI Symbol Slc30a4
EMBL AL772253
GenPept
RNA Seq Atlas 22785

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca