Version 5.4
Mus musculus Gene: Uhmk1
Summary
InnateDB Gene IDBG-203692.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Uhmk1
Gene Name U2AF homology motif (UHM) kinase 1
Synonyms 4732477C12Rik; 4930500M09Rik; AA673513; AI449218; AU021979; KIS; Kist; P-CIP2
Species Mus musculus
Ensembl Gene ENSMUSG00000026667
Encoded Proteins
IDBP-203694
U2AF homology motif (UHM) kinase 1
IDBP-539333
U2AF homology motif (UHM) kinase 1
IDBP-536183
U2AF homology motif (UHM) kinase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152332:
The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:170193420-170215397
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000027979 ENSMUSP00000027979
ENSMUST00000150821 ENSMUSP00000115622
ENSMUST00000123399 ENSMUSP00000120787
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019899 enzyme binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007050 cell cycle arrest
GO:0018105 peptidyl-serine phosphorylation
GO:0031175 neuron projection development
GO:0045948 positive regulation of translational initiation
GO:0046777 protein autophosphorylation
GO:0046825 regulation of protein export from nucleus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030424 axon
GO:0032839 dendrite cytoplasm
GO:0071598 neuronal ribonucleoprotein granule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000152332
View Gene Order
ENSBTAG00000012694
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.209150 Mm.486991
RefSeq NM_010633 XM_006496682
OMIM
CCDS CCDS15468
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca