Version 5.4
Mus musculus Gene: Crlf3
Summary
InnateDB Gene IDBG-203825.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crlf3
Gene Name cytokine receptor-like factor 3
Synonyms BB164954; Creme9; Cytor4
Species Mus musculus
Ensembl Gene ENSMUSG00000017561
Encoded Proteins
IDBP-203827
cytokine receptor-like factor 3
IDBP-203829
cytokine receptor-like factor 3
IDBP-717845
IDBP-718049
IDBP-717356
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a cytokine receptor-like factor that contains a fibronectin type 3 domain. The encoded protein may act as a negative regulator of the cell cycle. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:80046493-80080991
Strand Reverse strand
Band B5
Transcripts
ENSMUST00000103233 ENSMUSP00000099523
ENSMUST00000061283 ENSMUSP00000060028
ENSMUST00000092858
ENSMUST00000147164
ENSMUST00000177825 ENSMUSP00000136473
ENSMUST00000178893 ENSMUSP00000137371
ENSMUST00000178280
ENSMUST00000179855 ENSMUSP00000137124
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0030308 negative regulation of cell growth
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046427 positive regulation of JAK-STAT cascade
GO:0071158 positive regulation of cell cycle arrest
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000176390
View Gene Order
ENSBTAG00000018381
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.272093 Mm.465832
RefSeq NM_001277106 NM_018776
OMIM
CCDS CCDS25126 CCDS70260
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca