Version 5.4
Mus musculus Gene: Fcgr3
Summary
InnateDB Gene IDBG-204038.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fcgr3
Gene Name Fc receptor, IgG, low affinity III
Synonyms CD16
Species Mus musculus
Ensembl Gene ENSMUSG00000059498
Encoded Proteins
IDBP-621706
Fc receptor, IgG, low affinity III
IDBP-621708
Fc receptor, IgG, low affinity III
IDBP-621709
Fc receptor, IgG, low affinity III
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:171051174-171064935
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000168817
ENSMUST00000164044 ENSMUSP00000131938
ENSMUST00000169017 ENSMUSP00000131836
ENSMUST00000164179 ENSMUSP00000133039
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019770 IgG receptor activity
GO:0019864 IgG binding
Biological Process
GO:0001788 antibody-dependent cellular cytotoxicity
GO:0001798 positive regulation of type IIa hypersensitivity
GO:0001805 positive regulation of type III hypersensitivity
GO:0001812 positive regulation of type I hypersensitivity
GO:0001820 serotonin secretion
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0007166 cell surface receptor signaling pathway
GO:0030593 neutrophil chemotaxis
GO:0038094 Fc-gamma receptor signaling pathway
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0045576 mast cell activation
GO:0050766 positive regulation of phagocytosis
GO:0050776 regulation of immune response
Cellular Component
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu05150
Staphylococcus aureus infection pathway
mmu05140
Leishmaniasis pathway
mmu04380
Osteoclast differentiation pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.22119 Mm.480161
RefSeq NM_010188 XM_006496658 XM_006496659 XM_006496660 XM_006496661
OMIM
CCDS CCDS15477
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca