Version 5.4
Mus musculus Protein: Fcgr3
Summary
InnateDB Protein IDBP-621708.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fcgr3
Protein Name Fc receptor, IgG, low affinity III
Synonyms CD16;
Species Mus musculus
Ensembl Protein ENSMUSP00000131836
InnateDB Gene IDBG-204038 (Fcgr3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019770 IgG receptor activity
GO:0019864 IgG binding
Biological Process
GO:0001788 antibody-dependent cellular cytotoxicity
GO:0001798 positive regulation of type IIa hypersensitivity
GO:0001805 positive regulation of type III hypersensitivity
GO:0001812 positive regulation of type I hypersensitivity
GO:0001820 serotonin secretion
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0007166 cell surface receptor signaling pathway
GO:0030593 neutrophil chemotaxis
GO:0038094 Fc-gamma receptor signaling pathway
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0045576 mast cell activation
GO:0050766 positive regulation of phagocytosis
GO:0050776 regulation of immune response
Cellular Component
Protein Structure and Domains
PDB ID MGI:95500
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PVR4
UniProt Splice Variant
Entrez Gene 14131
UniGene Mm.480161
RefSeq
MGI ID
MGI Symbol Fcgr3
OMIM
CCDS
HPRD
IMGT
EMBL AC115959 AC117796
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca