Mus musculus Gene: Polr2j
Summary
InnateDB Gene IDBG-204364.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Polr2j
Gene Name polymerase (RNA) II (DNA directed) polypeptide J
Synonyms 14.5kDa; Polr2i; Rpb11a; Rpo2-4
Species Mus musculus
Ensembl Gene ENSMUSG00000039771
Encoded Proteins
polymerase (RNA) II (DNA directed) polypeptide J
polymerase (RNA) II (DNA directed) polypeptide J
polymerase (RNA) II (DNA directed) polypeptide J
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000005075:
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:136116631-136122947
Strand Forward strand
Band G2
Transcripts
ENSMUST00000041366 ENSMUSP00000038505
ENSMUST00000111129 ENSMUSP00000106759
ENSMUST00000111127 ENSMUSP00000106757
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030275 LRR domain binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005665 DNA-directed RNA polymerase II, core complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Pyrimidine metabolism pathway
RNA polymerase pathway
Purine metabolism pathway
Huntington's disease pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Tat-mediated HIV elongation arrest and recovery pathway
Pausing and recovery of Tat-mediated HIV elongation pathway
Viral Messenger RNA Synthesis pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing - Minor Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Capping pathway
MicroRNA (miRNA) biogenesis pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
Formation of RNA Pol II elongation complex pathway
Formation of the Early Elongation Complex pathway
RNA Polymerase II Transcription Elongation pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
Formation of HIV elongation complex in the absence of HIV Tat pathway
HIV Transcription Initiation pathway
Pausing and recovery of HIV elongation pathway
RNA Polymerase II HIV Promoter Escape pathway
Formation of the HIV-1 Early Elongation Complex pathway
Formation of HIV-1 elongation complex containing HIV-1 Tat pathway
Tat-mediated elongation of the HIV-1 transcript pathway
Abortive elongation of HIV-1 transcript in the absence of Tat pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
HIV elongation arrest and recovery pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
Dual incision reaction in TC-NER pathway
Transcription-coupled NER (TC-NER) pathway
Influenza Infection pathway
Transcriptional regulation by small RNAs pathway
Influenza Viral RNA Transcription and Replication pathway
HIV Transcription Elongation pathway
RNA Polymerase II Transcription pathway
HIV Life Cycle pathway
HIV Infection pathway
Influenza Life Cycle pathway
mRNA Splicing pathway
Nucleotide Excision Repair pathway
Gene Expression pathway
Disease pathway
DNA Repair pathway
Regulatory RNA pathways pathway
RNA Polymerase II Transcription pathway
mRNA Capping pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing pathway
Transcription-coupled NER (TC-NER) pathway
RNA Polymerase II Pre-transcription Events pathway
RNA Polymerase II Promoter Escape pathway
Gene Expression pathway
Nucleotide Excision Repair pathway
Transcriptional regulation by small RNAs pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
RNA Polymerase II Transcription Elongation pathway
DNA Repair pathway
Dual incision reaction in TC-NER pathway
Formation of RNA Pol II elongation complex pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
mRNA Splicing - Minor Pathway pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Polymerase II Transcription Initiation pathway
Regulatory RNA pathways pathway
Formation of the Early Elongation Complex pathway
KEGG
Pyrimidine metabolism pathway
Purine metabolism pathway
RNA polymerase pathway
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3YZ19
UniProt Splice Variant
Entrez Gene 20022
UniGene Mm.4896
RefSeq NM_011293
OMIM
CCDS CCDS19751
HPRD
IMGT
MGI ID MGI:109582
MGI Symbol Polr2j
EMBL AC087420
GenPept
RNA Seq Atlas 20022