InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Pfdn2

Summary

InnateDB Gene

IDBG-204479.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pfdn2

Gene Name

prefoldin 2

Synonyms

ESTM27; W48336

Species

Mus musculus

Ensembl Gene

ENSMUSG00000006412

Encoded Proteins

IDBP-204481

prefoldin 2

IDBP-540898

prefoldin 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143256:
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:171345670-171359254

Strand

Forward strand

Band

Transcripts

ENSMUST00000006579	ENSMUSP00000006579
ENSMUST00000135941	ENSMUSP00000120106
ENSMUST00000138323

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding
GO:0051082	unfolded protein binding

Biological Process

GO:0006457

protein folding

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0016272	prefoldin complex
GO:0070062	extracellular vesicular exosome