Version 5.4
Mus musculus Gene: Ccl11
Summary
InnateDB Gene IDBG-204519.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccl11
Gene Name chemokine (C-C motif) ligand 11
Synonyms eotaxin; Scya11
Species Mus musculus
Ensembl Gene ENSMUSG00000020676
Encoded Proteins
IDBP-204521
chemokine (C-C motif) ligand 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:82057823-82062955
Strand Forward strand
Band C
Transcripts
ENSMUST00000000342 ENSMUSP00000000342
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008009 chemokine activity
Biological Process
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002544 chronic inflammatory response
GO:0002551 mast cell chemotaxis
GO:0006955 immune response
GO:0007010 cytoskeleton organization
GO:0007015 actin filament organization
GO:0008360 regulation of cell shape
GO:0030335 positive regulation of cell migration
GO:0030838 positive regulation of actin filament polymerization
GO:0032855 positive regulation of Rac GTPase activity
GO:0045766 positive regulation of angiogenesis
GO:0048245 eosinophil chemotaxis
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060763 mammary duct terminal end bud growth
GO:0070371 ERK1 and ERK2 cascade
GO:0070670 response to interleukin-4
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_230248
Chemokine receptors bind chemokines pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
mmu05310
Asthma pathway
mmu04062
Chemokine signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt P48298
TrEMBL
UniProt Splice Variant
Entrez Gene 20292
UniGene Mm.4686
RefSeq NM_011330
OMIM
CCDS CCDS36246
HPRD
IMGT
MGI ID MGI:103576
MGI Symbol Ccl11
EMBL AF128205 AF128206 AF128207 AF128208 AF128209 AK010146 BC027521 U26426 U40672 U77462
GenPept AAA99776 AAC52256 AAC53321 AAF22546 AAF22547 AAF22548 AAF22549 AAF22550 AAH27521 BAB26731
RNA Seq Atlas 20292

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca