Mus musculus Gene: Srm
Summary
InnateDB Gene IDBG-204691.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Srm
Gene Name spermidine synthase
Synonyms AA407669; SpdST; SpdSy
Species Mus musculus
Ensembl Gene ENSMUSG00000006442
Encoded Proteins
spermidine synthase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116649:
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:148591503-148594993
Strand Forward strand
Band E2
Transcripts
ENSMUST00000006611 ENSMUSP00000006611
ENSMUST00000152701
ENSMUST00000140129
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004766 spermidine synthase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0008295 spermidine biosynthetic process
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Metabolism pathway
Metabolism of amino acids and derivatives pathway
Metabolism of polyamines pathway
KEGG
beta-Alanine metabolism pathway
Glutathione metabolism pathway
Arginine and proline metabolism pathway
Cysteine and methionine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of polyamines pathway
Metabolism of amino acids and derivatives pathway
Metabolism pathway
KEGG
Arginine and proline metabolism pathway
Glutathione metabolism pathway
beta-Alanine metabolism pathway
Cysteine and methionine metabolism pathway
INOH
Arginine Proline metabolism pathway
PID NCI
Cross-References
SwissProt Q64674
TrEMBL Q543H0
UniProt Splice Variant
Entrez Gene 20810
UniGene Mm.10
RefSeq NM_009272
OMIM
CCDS CCDS18940
HPRD
IMGT
MGI ID MGI:102690
MGI Symbol Srm
EMBL AK051101 BC005566 CH466594 L19311 Z67748
GenPept AAC37666 AAH05566 BAC34526 CAA91561 EDL14826
RNA Seq Atlas 20810