Version 5.4
Mus musculus Gene: Prkcdbp
Summary
InnateDB Gene IDBG-204708.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prkcdbp
Gene Name protein kinase C, delta binding protein
Synonyms 3110015B12Rik; 6330514M23Rik; SRBC
Species Mus musculus
Ensembl Gene ENSMUSG00000037060
Encoded Proteins
IDBP-204710
protein kinase C, delta binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170955:
The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:105480607-105482197
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000047040 ENSMUSP00000044979
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005080 protein kinase C binding
GO:0005515 protein binding
Biological Process
GO:0030866 cortical actin cytoskeleton organization
GO:0051898 negative regulation of protein kinase B signaling
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1901003 negative regulation of fermentation
Cellular Component
GO:0005901 caveola
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000170955
View Gene Order
ENSBTAG00000019754
Not yet available
Cross-References
SwissProt Q91VJ2
TrEMBL
UniProt Splice Variant
Entrez Gene 109042
UniGene
RefSeq NM_028444
OMIM
CCDS CCDS21652
HPRD
IMGT
MGI ID MGI:1923422
MGI Symbol Prkcdbp
EMBL AK014051 AK032154 BC009660
GenPept AAH09660 BAB29133 BAC27728
RNA Seq Atlas 109042

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca