Version 5.4
Homo sapiens Gene: PRKCDBP
Summary
InnateDB Gene IDBG-28654.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRKCDBP
Gene Name protein kinase C, delta binding protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170955
Encoded Proteins
IDBP-28656
protein kinase C, delta binding protein
IDBP-597700
protein kinase C, delta binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:6318946-6320647
Strand Reverse strand
Band p15.4
Transcripts
ENST00000303927 ENSP00000307292
ENST00000532354
ENST00000524852
ENST00000530979 ENSP00000432047
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005080 protein kinase C binding
GO:0005515 protein binding
Biological Process
GO:0030866 cortical actin cytoskeleton organization
GO:0051898 negative regulation of protein kinase B signaling
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1901003 negative regulation of fermentation
Cellular Component
GO:0005901 caveola
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037060
View Gene Order
ENSBTAG00000019754
Not yet available
Cross-References
SwissProt Q969G5
TrEMBL
UniProt Splice Variant
Entrez Gene 112464
UniGene
RefSeq NM_145040
HUGO HGNC:9400
OMIM
CCDS CCDS7762
HPRD 17908
IMGT
EMBL AC068733 AF339881 AF408198 BC011585 CH471064
GenPept AAH11585 AAK97528 AAK97572 EAW68733
RNA Seq Atlas 112464

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca