Mus musculus Gene: Pigm
Summary
InnateDB Gene IDBG-205452.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigm
Gene Name phosphatidylinositol glycan anchor biosynthesis, class M
Synonyms 4933437L05Rik; AI644422; AV302080; C920011G20Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000050229
Encoded Proteins
phosphatidylinositol glycan anchor biosynthesis, class M
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143315:
This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:172376531-172384099
Strand Forward strand
Band H3
Transcripts
ENSMUST00000052455 ENSMUSP00000052838
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000030 mannosyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
Biological Process
GO:0006506 GPI anchor biosynthetic process
GO:0097502 mannosylation
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of glycosylphosphatidylinositol (GPI) pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q8C2R7
TrEMBL
UniProt Splice Variant
Entrez Gene 67556
UniGene Mm.26612 Mm.404850 Mm.405312 Mm.444902
RefSeq NM_026234
OMIM
CCDS CCDS15513
HPRD
IMGT
MGI ID MGI:1914806
MGI Symbol Pigm
EMBL AK018560 AK040397 AK043216 AK080242 AK088117 BC005650 BC083115
GenPept AAH05650 AAH83115 BAB31275 BAC30585 BAC31497 BAC37857 BAC40156
RNA Seq Atlas 67556