Version 5.4
Mus musculus Protein: Pigm
Summary
InnateDB Protein IDBP-205454.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigm
Protein Name phosphatidylinositol glycan anchor biosynthesis, class M
Synonyms 4933437L05Rik; AI644422; AV302080; C920011G20Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000052838
InnateDB Gene IDBG-205452 (Pigm)
Protein Structure
UniProt Annotation
Function Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000030 mannosyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
Biological Process
GO:0006506 GPI anchor biosynthetic process
GO:0097502 mannosylation
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1914806
InterPro IPR007704 Mannosyltransferase, DXD
PFAM PF05007
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C2R7
PhosphoSite PhosphoSite-Q8C2R7
TrEMBL
UniProt Splice Variant
Entrez Gene 67556
UniGene Mm.444902
RefSeq NP_080510
MGI ID
MGI Symbol Pigm
OMIM
CCDS CCDS15513
HPRD
IMGT
EMBL AK018560 AK040397 AK043216 AK080242 AK088117 BC005650 BC083115
GenPept AAH05650 AAH83115 BAB31275 BAC30585 BAC31497 BAC37857 BAC40156

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca