Version 5.4
Mus musculus Gene: H6pd
Summary
InnateDB Gene IDBG-205502.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H6pd
Gene Name hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Synonyms AI785303; G6pd1; Gpd-1; Gpd1
Species Mus musculus
Ensembl Gene ENSMUSG00000028980
Encoded Proteins
IDBP-205506
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
IDBP-205508
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
IDBP-536236
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000049239:
There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:149979475-150009023
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000030830 ENSMUSP00000030830
ENSMUST00000084117 ENSMUSP00000081134
ENSMUST00000153394 ENSMUSP00000115647
ENSMUST00000152907
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004345 glucose-6-phosphate dehydrogenase activity
GO:0017057 6-phosphogluconolactonase activity
GO:0030246 carbohydrate binding
GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity
GO:0050661 NADP binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
GO:0006098 pentose-phosphate shunt
GO:0006739 NADP metabolic process
GO:0055114 oxidation-reduction process
GO:0097305 response to alcohol
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005788 endoplasmic reticulum lumen
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000049239
View Gene Order
ENSBTAG00000004246
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00030
Pentose phosphate pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00030
Pentose phosphate pathway pathway
INOH
INOH website
Pentose phosphate cycle pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.22183 Mm.404199 Mm.488650
RefSeq NM_001291004 NM_173371 XM_006537059 XM_006537061 XM_006538458 XM_006538459 XM_006538460 XM_006538461
OMIM
CCDS CCDS18967 CCDS71524
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca