Version 5.4
Mus musculus Gene: Slamf8
Summary
InnateDB Gene IDBG-205620.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slamf8
Gene Name SLAM family member 8
Synonyms 5830408F06Rik; Blame; SBBI42
Species Mus musculus
Ensembl Gene ENSMUSG00000053318
Encoded Proteins
IDBP-205622
SLAM family member 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 18501771
[Homo sapiens] The SLAM and SAP gene families control innate and adaptive immune responses
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158714:
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:172581377-172590568
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000065679 ENSMUSP00000067527
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0033860 regulation of NAD(P)H oxidase activity
GO:0035690 cellular response to drug
GO:0042742 defense response to bacterium
GO:0043549 regulation of kinase activity
GO:0090383 phagosome acidification
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000158714
View Gene Order
ENSBTAG00000016698
Not yet available
Cross-References
SwissProt
TrEMBL Q3UQA2
UniProt Splice Variant
Entrez Gene 74748
UniGene Mm.179812
RefSeq NM_029084
OMIM
CCDS CCDS15517
HPRD
IMGT
MGI ID MGI:1921998
MGI Symbol Slamf8
EMBL AC131177 AK142633
GenPept BAE25140
RNA Seq Atlas 74748

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca