Version 5.4
Mus musculus Gene: Zkscan1
Summary
InnateDB Gene IDBG-205713.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zkscan1
Gene Name zinc finger with KRAB and SCAN domains 1
Synonyms 5930429A01Rik; 9130423L19Rik; 9230118B16Rik; AI646829; AI788588; C87323; KOX18; PHZ-37; ZNF139
Species Mus musculus
Ensembl Gene ENSMUSG00000029729
Encoded Proteins
IDBP-205715
zinc finger with KRAB and SCAN domains 1
IDBP-205717
zinc finger with KRAB and SCAN domains 1
IDBP-259133
zinc finger with KRAB and SCAN domains 1
IDBP-259135
zinc finger with KRAB and SCAN domains 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106261:
The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:138085084-138107822
Strand Forward strand
Band G2
Transcripts
ENSMUST00000019660 ENSMUSP00000019660
ENSMUST00000066617 ENSMUSP00000068480
ENSMUST00000110963 ENSMUSP00000106588
ENSMUST00000110962 ENSMUSP00000106587
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000106261
View Gene Order
ENSBTAG00000016757
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BGS3
TrEMBL
UniProt Splice Variant
Entrez Gene 74570
UniGene Mm.213114 Mm.399654
RefSeq NM_133906 NM_029869 XM_006504628
OMIM
CCDS CCDS19789 CCDS19788
HPRD
IMGT
MGI ID MGI:1921820
MGI Symbol Zkscan1
EMBL AK020039 AK028932 AK031759 AK036807 AK054323 AK131148 AK135999 BC052441
GenPept AAH52441 BAB31975 BAC26200 BAC27539 BAC29584 BAC35730 BAD21398 BAE22767
RNA Seq Atlas 74570

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca