Homo sapiens Gene: ZKSCAN1
Summary
InnateDB Gene IDBG-30234.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZKSCAN1
Gene Name zinc finger with KRAB and SCAN domains 1
Synonyms 9130423L19Rik; KOX18; PHZ-37; ZNF139; ZNF36; ZSCAN33
Species Homo sapiens
Ensembl Gene ENSG00000106261
Encoded Proteins
zinc finger with KRAB and SCAN domains 1
zinc finger with KRAB and SCAN domains 1
zinc finger with KRAB and SCAN domains 1
zinc finger with KRAB and SCAN domains 1
zinc finger with KRAB and SCAN domains 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:100015572-100041689
Strand Forward strand
Band q22.1
Transcripts
ENST00000324306 ENSP00000323148
ENST00000426572 ENSP00000409172
ENST00000432317 ENSP00000394445
ENST00000482979
ENST00000535170 ENSP00000443508
ENST00000620510 ENSP00000480305
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Generic Transcription Pathway pathway
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001287054 NM_001287055 NM_003439 XM_006716112
HUGO
OMIM
CCDS CCDS34698 CCDS69349 CCDS75640
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas