Version 5.4
Mus musculus Gene: Slc4a11
Summary
InnateDB Gene IDBG-206678.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc4a11
Gene Name solute carrier family 4, sodium bicarbonate transporter-like, member 11
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000074796
Encoded Proteins
IDBP-206680
solute carrier family 4, sodium bicarbonate transporter-like, member 11
IDBP-532456
solute carrier family 4, sodium bicarbonate transporter-like, member 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088836:
This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:130684113-130697519
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000099362 ENSMUSP00000096963
ENSMUST00000144945
ENSMUST00000134647
ENSMUST00000138028
ENSMUST00000127397 ENSMUSP00000117976
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005452 inorganic anion exchanger activity
GO:0008509 anion transmembrane transporter activity
GO:0015293 symporter activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006810 transport
GO:0006820 anion transport
GO:0042044 fluid transport
GO:0050801 ion homeostasis
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000088836
View Gene Order
ENSBTAG00000027409
Not yet available
Cross-References
SwissProt
TrEMBL A2AJN8
UniProt Splice Variant
Entrez Gene 269356
UniGene Mm.404246 Mm.441391
RefSeq NM_001081162
OMIM
CCDS CCDS38244
HPRD
IMGT
MGI ID MGI:2138987
MGI Symbol Slc4a11
EMBL AL772162
GenPept
RNA Seq Atlas 269356

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca