InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gna12

Summary

InnateDB Gene

IDBG-207106.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gna12

Gene Name

guanine nucleotide binding protein, alpha 12

Synonyms

AI414047; AI504261; Galpha12

Species

Mus musculus

Ensembl Gene

ENSMUSG00000000149

Encoded Proteins

IDBP-207108

guanine nucleotide binding protein, alpha 12

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146535:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:140758408-140830431

Strand

Reverse strand

Band

Transcripts

ENSMUST00000000153

ENSMUSP00000000153

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0031752	D5 dopamine receptor binding
GO:0046872	metal ion binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007266	Rho protein signal transduction
GO:0008360	regulation of cell shape
GO:0010762	regulation of fibroblast migration
GO:0030154	cell differentiation
GO:0032006	regulation of TOR signaling
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556	intracellular signal transduction
GO:0042493	response to drug
GO:0042733	embryonic digit morphogenesis