Bos taurus Gene: GNA12
Summary
InnateDB Gene IDBG-641207.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GNA12
Gene Name guanine nucleotide-binding protein subunit alpha-12
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017871
Encoded Proteins
guanine nucleotide binding protein (G protein) alpha 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146535:
Gene Information
Type Protein coding
Genomic Location Chromosome 25:41099259-41171209
Strand Forward strand
Band
Transcripts
ENSBTAT00000023757 ENSBTAP00000023757
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0001664 G-protein coupled receptor binding
GO:0003924 GTPase activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019001 guanyl nucleotide binding
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0031752 D5 dopamine receptor binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0007266 Rho protein signal transduction
GO:0008360 regulation of cell shape
GO:0010762 regulation of fibroblast migration
GO:0030154 cell differentiation
GO:0032006 regulation of TOR signaling
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 intracellular signal transduction
GO:0042733 embryonic digit morphogenesis
Cellular Component
GO:0005834 heterotrimeric G-protein complex
GO:0031526 brush border membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
TSH pathway
REACTOME
Thrombin signalling through proteinase activated receptors (PARs) pathway
G alpha (12/13) signalling events pathway
Signaling by GPCR pathway
Platelet activation, signaling and aggregation pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Hemostasis pathway
GPCR downstream signaling pathway
Hemostasis pathway
Signaling by GPCR pathway
Platelet activation, signaling and aggregation pathway
G alpha (12/13) signalling events pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Signal Transduction pathway
KEGG
Regulation of actin cytoskeleton pathway
MAPK signaling pathway pathway
Long-term depression pathway
Vascular smooth muscle contraction pathway
Regulation of actin cytoskeleton pathway
MAPK signaling pathway pathway
Long-term depression pathway
Vascular smooth muscle contraction pathway
INOH
PID NCI
Sphingosine 1-phosphate (S1P) pathway
LPA receptor mediated events
S1P2 pathway
PAR1-mediated thrombin signaling events
Endothelins
S1P5 pathway
S1P3 pathway
S1P4 pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.105305
RefSeq NM_001192401
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas