Version 5.4
Mus musculus Gene: Pex10
Summary
InnateDB Gene IDBG-207425.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pex10
Gene Name peroxisomal biogenesis factor 10
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029047
Encoded Proteins
IDBP-207427
peroxisomal biogenesis factor 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157911:
This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:155067016-155072433
Strand Forward strand
Band E2
Transcripts
ENSMUST00000103180 ENSMUSP00000099469
ENSMUST00000123395
ENSMUST00000125432
ENSMUST00000133116
ENSMUST00000134341
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0007031 peroxisome organization
GO:0016558 protein import into peroxisome matrix
Cellular Component
GO:0005622 intracellular
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000157911
View Gene Order
ENSBTAG00000009309
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04146
Peroxisome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt B1AUE5
TrEMBL
UniProt Splice Variant
Entrez Gene 668173
UniGene Mm.133114
RefSeq NM_001042407
OMIM
CCDS CCDS19021
HPRD
IMGT
MGI ID MGI:2684988
MGI Symbol Pex10
EMBL AL670413 BC147304 BC147305 CH466594
GenPept AAI47305 AAI47306 CAM20044 EDL14991
RNA Seq Atlas 668173

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca