Version 5.4
Homo sapiens Gene: ARIH1
Summary
InnateDB Gene IDBG-20750.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARIH1
Gene Name ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
Synonyms ARI; HARI; HHARI; UBCH7BP
Species Homo sapiens
Ensembl Gene ENSG00000166233
Encoded Proteins
IDBP-20754
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
IDBP-813437
ariadne RBR E3 ubiquitin protein ligase 1
IDBP-745665
IDBP-744947
IDBP-744802
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:72474326-72602985
Strand Forward strand
Band q24.1
Transcripts
ENST00000379887 ENSP00000369217
ENST00000562891 ENSP00000477687
ENST00000570085 ENSP00000456746
ENST00000566063
ENST00000565950
ENST00000561987
ENST00000561770 ENSP00000457767
ENST00000567762
ENST00000564062 ENSP00000454774
ENST00000563310
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 45 [view]
Protein-Protein 45 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0019787 small conjugating protein ligase activity
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016567 protein ubiquitination
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025234
View Gene Order
ENSBTAG00000006708
Not yet available
Pathways
NETPATH
REACTOME
REACT_115831
ISG15 antiviral mechanism pathway
REACT_115676
Antiviral mechanism by IFN-stimulated genes pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_25229
Interferon Signaling pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.268787 Hs.614624 Hs.629162
RefSeq NM_005744
HUGO
OMIM
CCDS CCDS10244
HPRD 05730
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca