Version 5.4
Mus musculus Gene: Enah
Summary
InnateDB Gene IDBG-207633.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Enah
Gene Name enabled homolog (Drosophila)
Synonyms Mena; NDPP-1; Ndpp1; WBP8
Species Mus musculus
Ensembl Gene ENSMUSG00000022995
Encoded Proteins
IDBP-207635
enabled homolog (Drosophila)
IDBP-258974
enabled homolog (Drosophila)
IDBP-258978
enabled homolog (Drosophila)
IDBP-258980
enabled homolog (Drosophila)
IDBP-716979
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154380:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:181904445-182019980
Strand Reverse strand
Band H5
Transcripts
ENSMUST00000078719 ENSMUSP00000077781
ENSMUST00000111030 ENSMUSP00000106659
ENSMUST00000111025 ENSMUSP00000106654
ENSMUST00000111024 ENSMUSP00000106653
ENSMUST00000177811 ENSMUSP00000136863
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005522 profilin binding
GO:0017124 SH3 domain binding
GO:0050699 WW domain binding
Biological Process
GO:0001843 neural tube closure
GO:0006928 cellular component movement
GO:0007015 actin filament organization
GO:0007411 axon guidance
GO:0008154 actin polymerization or depolymerization
GO:0030036 actin cytoskeleton organization
GO:0046907 intracellular transport
Cellular Component
GO:0001725 stress fiber
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030175 filopodium
GO:0045202 synapse
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000154380
View Gene Order
ENSBTAG00000016185
Not yet available
Pathways
NETPATH
REACTOME
REACT_230745
Immune System pathway
REACT_221567
Signaling by Robo receptor pathway
REACT_261444
Axon guidance pathway
REACT_229531
Adaptive Immune System pathway
REACT_188576
Developmental Biology pathway
REACT_225768
Generation of second messenger molecules pathway
REACT_222648
TCR signaling pathway
KEGG
mmu04810
Regulation of actin cytoskeleton pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
REACT_12623
Generation of second messenger molecules pathway
REACT_19351
Signaling by Robo receptor pathway
REACT_111045
Developmental Biology pathway
REACT_12526
TCR signaling pathway
REACT_18266
Axon guidance pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
INOH
PID NCI
ecadherin_nascentaj_pathway
E-cadherin signaling in the nascent adherens junction
cdc42_pathway
CDC42 signaling events
ecadherin_stabilization_pathway
Stabilization and expansion of the E-cadherin adherens junction
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.389224
RefSeq NM_001083120 NM_001083121 NM_008680 NM_010135
OMIM
CCDS CCDS35811 CCDS48473 CCDS48474
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca