Mus musculus Gene: Degs1 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-207682.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Degs1 | ||||||||
Gene Name | degenerative spermatocyte homolog 1 (Drosophila) | ||||||||
Synonyms | AA536663; Degs; Des1; Mdes | ||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000038633 | ||||||||
Encoded Proteins |
degenerative spermatocyte homolog 1 (Drosophila)
degenerative spermatocyte homolog 1 (Drosophila)
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143753:
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 1:182275772-182282804 | ||||||||
Strand | Reverse strand | ||||||||
Band | H5 | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||
NETPATH | |||||||||
REACTOME |
Sphingolipid de novo biosynthesis pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
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KEGG |
Sphingolipid metabolism pathway
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INOH | |||||||||
PID NCI | |||||||||
Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Sphingolipid de novo biosynthesis pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Sphingolipid de novo biosynthesis pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
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KEGG |
Sphingolipid metabolism pathway
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INOH | |||||||||
PID NCI | |||||||||
Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Mm.29648 Mm.466933 | ||||||||
RefSeq | NM_007853 | ||||||||
OMIM | |||||||||
CCDS | CCDS15587 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | |||||||||
MGI Symbol | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||