Version 5.4
| Mus musculus Protein: Degs1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-207684.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Degs1 | ||||||||
| Protein Name | degenerative spermatocyte homolog 1 (Drosophila) | ||||||||
| Synonyms | AA536663; Degs; Des1; Mdes; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000048519 | ||||||||
| InnateDB Gene | IDBG-207682 (Degs1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). {ECO:0000269PubMed:11937514}. | ||||||||
| Subcellular Localization | Mitochondrion. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Detected in testis. Detected in pachytene spermatocytes and round spermatids. {ECO:0000269PubMed:9227906}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1097711 | ||||||||
| InterPro |
IPR005804
Fatty acid desaturase, type 1 IPR011388 Sphingolipid delta4-desaturase IPR013866 Sphingolipid delta4-desaturase, N-terminal |
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| PFAM |
PF00487
PF08557 |
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| PRINTS | |||||||||
| PIRSF |
PIRSF017228
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| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | O09005 | ||||||||
| PhosphoSite | PhosphoSite-O09005 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 13244 | ||||||||
| UniGene | Mm.466933 | ||||||||
| RefSeq | NP_031879 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Degs1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS15587 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF466376 AK002617 AK077257 AK149811 AK163404 BC003751 Y08460 | ||||||||
| GenPept | AAH03751 AAM12532 BAB22233 BAC36713 BAE29098 BAE37337 CAA69714 | ||||||||