Version 5.4
| Mus musculus Gene: Plcb4 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-207722.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Plcb4 | ||||||||||||||||||||||
| Gene Name | phospholipase C, beta 4 | ||||||||||||||||||||||
| Synonyms | A930039J07Rik; AI854601; C230058B11Rik | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000039943 | ||||||||||||||||||||||
| Encoded Proteins |
phospholipase C, beta 4
phospholipase C, beta 4
phospholipase C, beta 4
phospholipase C, beta 4
phospholipase C, beta 4
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| Protein Structure | |||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101333:
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 2:135659011-136014593 | ||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||
| Band | F3 | ||||||||||||||||||||||
| Transcripts | |||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME | |||||||||||||||||||||||
| KEGG |
Calcium signaling pathway pathway
Alzheimer's disease pathway
Melanogenesis pathway
Wnt signaling pathway pathway
Gap junction pathway
Phosphatidylinositol signaling system pathway
GnRH signaling pathway pathway
Long-term potentiation pathway
Long-term depression pathway
Inositol phosphate metabolism pathway
Chemokine signaling pathway pathway
Vascular smooth muscle contraction pathway
Huntington's disease pathway
Amoebiasis pathway
Gastric acid secretion pathway
Salivary secretion pathway
Pancreatic secretion pathway
Chagas disease (American trypanosomiasis) pathway
African trypanosomiasis pathway
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| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
PLC beta mediated events pathway
Opioid Signalling pathway
Synthesis of IP3 and IP4 in the cytosol pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G-protein mediated events pathway
Inositol phosphate metabolism pathway
Metabolism pathway
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| KEGG |
GnRH signaling pathway pathway
Gap junction pathway
Wnt signaling pathway pathway
Inositol phosphate metabolism pathway
Long-term potentiation pathway
Alzheimer's disease pathway
Phosphatidylinositol signaling system pathway
Long-term depression pathway
Calcium signaling pathway pathway
Melanogenesis pathway
Vascular smooth muscle contraction pathway
Chemokine signaling pathway pathway
Huntington's disease pathway
Gastric acid secretion pathway
Amoebiasis pathway
Chagas disease (American trypanosomiasis) pathway
Pancreatic secretion pathway
Salivary secretion pathway
African trypanosomiasis pathway
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| INOH |
GPCR GroupI metabotropic glutamate receptor signaling pathway pathway
GPCR signaling pathway
Inositol phosphate metabolism pathway
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| PID NCI | |||||||||||||||||||||||
| Cross-References | |||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| UniGene | Mm.38009 Mm.405299 | ||||||||||||||||||||||
| RefSeq | NM_013829 XM_006498936 XM_006498937 XM_006498938 XM_006498943 XM_006498944 XM_006498945 XM_006498946 XM_006498947 XM_006498948 XM_006498949 XM_006498950 XM_006498951 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS16788 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | |||||||||||||||||||||||
| MGI Symbol | |||||||||||||||||||||||
| EMBL | |||||||||||||||||||||||
| GenPept | |||||||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||||||