Version 5.4
Mus musculus Gene: Gprc5b
Summary
InnateDB Gene IDBG-207880.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gprc5b
Gene Name G protein-coupled receptor, family C, group 5, member B
Synonyms AW125761; Raig2
Species Mus musculus
Ensembl Gene ENSMUSG00000008734
Encoded Proteins
IDBP-207882
G protein-coupled receptor, family C, group 5, member B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167191:
The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:118972040-118995211
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000008878 ENSMUSP00000008878
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0019901 protein kinase binding
GO:0030295 protein kinase activator activity
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007626 locomotory behavior
GO:0010976 positive regulation of neuron projection development
GO:0042593 glucose homeostasis
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045666 positive regulation of neuron differentiation
GO:0045860 positive regulation of protein kinase activity
GO:0050729 positive regulation of inflammatory response
GO:0060907 positive regulation of macrophage cytokine production
GO:0061098 positive regulation of protein tyrosine kinase activity
GO:0090263 positive regulation of canonical Wnt signaling pathway
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0045121 membrane raft
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000167191
View Gene Order
ENSBTAG00000019596
Not yet available
Cross-References
SwissProt Q923Z0
TrEMBL Q9JMF0
UniProt Splice Variant
Entrez Gene 64297
UniGene Mm.103439 Mm.460323
RefSeq NM_001195774 NM_022420
OMIM
CCDS CCDS21777
HPRD
IMGT
MGI ID MGI:1927596
MGI Symbol Gprc5b
EMBL AB030197 AF378831 AK032047 BC020004
GenPept AAH20004 AAK58076 BAA92760 BAC27669
RNA Seq Atlas 64297

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca