Version 5.4
Mus musculus Gene: Ccnl2
Summary
InnateDB Gene IDBG-207914.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccnl2
Gene Name cyclin L2
Synonyms 1700010A01Rik; 1810019L15Rik; 2010319M22Rik; AA409936; Ania-6b; AW261738; HCLA-150; Pcee; SB138
Species Mus musculus
Ensembl Gene ENSMUSG00000029068
Encoded Proteins
IDBP-207916
cyclin L2
IDBP-536586
cyclin L2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000221978:
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:155812489-155824543
Strand Forward strand
Band E2
Transcripts
ENSMUST00000030944 ENSMUSP00000030944
ENSMUST00000139066
ENSMUST00000129850
ENSMUST00000136370
ENSMUST00000126346 ENSMUSP00000116000
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006396 RNA processing
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000221978
View Gene Order
ENSBTAG00000004873
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.23492 Mm.401542
RefSeq NM_207678
OMIM
CCDS CCDS19042
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca