Version 5.4
Mus musculus Gene: Rab3gap2
Summary
InnateDB Gene IDBG-207928.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rab3gap2
Gene Name RAB3 GTPase activating protein subunit 2
Synonyms 1110059F07Rik; 2010002H18Rik; 5830469C09; AI851069; AW743433; mKIAA0839; RAB3-GAP150
Species Mus musculus
Ensembl Gene ENSMUSG00000039318
Encoded Proteins
IDBP-207930
RAB3 GTPase activating protein subunit 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118873:
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:185204168-185286743
Strand Forward strand
Band H5
Transcripts
ENSMUST00000069652 ENSMUSP00000066325
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0043087 regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000118873
View Gene Order
ENSBTAG00000012585
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
botulinumtoxinpathway
Effects of Botulinum toxin
Cross-References
SwissProt
TrEMBL E9QKE4 Q3UEY3
UniProt Splice Variant
Entrez Gene 98732
UniGene Mm.275841 Mm.470378
RefSeq NM_001163754
OMIM
CCDS CCDS48478
HPRD
IMGT
MGI ID MGI:1916043
MGI Symbol Rab3gap2
EMBL AC129195 AC131084 AC158963 AK149265
GenPept BAE28778
RNA Seq Atlas 98732

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca