Version 5.4
Mus musculus Gene: Mrps23
Summary
InnateDB Gene IDBG-207937.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrps23
Gene Name mitochondrial ribosomal protein S23
Synonyms D11Bwg1153e; MRP-S23; Rpms23; S23mt
Species Mus musculus
Ensembl Gene ENSMUSG00000023723
Encoded Proteins
IDBP-207939
mitochondrial ribosomal protein S23
IDBP-265659
mitochondrial ribosomal protein S23
IDBP-400090
mitochondrial ribosomal protein S23
IDBP-532948
mitochondrial ribosomal protein S23
IDBP-537757
mitochondrial ribosomal protein S23
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181610:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:88204388-88211507
Strand Forward strand
Band C
Transcripts
ENSMUST00000024486 ENSMUSP00000024486
ENSMUST00000107915 ENSMUSP00000103548
ENSMUST00000118784 ENSMUSP00000113512
ENSMUST00000139170 ENSMUSP00000117416
ENSMUST00000144070 ENSMUSP00000122963
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0031965 nuclear membrane
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000181610
View Gene Order
ENSBTAG00000012366
Not yet available
Pathways
NETPATH
REACTOME
REACT_268789
Mitochondrial translation pathway
REACT_224594
Organelle biogenesis and maintenance pathway
REACT_270125
Mitochondrial translation elongation pathway
REACT_271096
Mitochondrial translation initiation pathway
REACT_270158
Mitochondrial translation termination pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_267673
Mitochondrial translation pathway
REACT_267680
Mitochondrial translation initiation pathway
REACT_267602
Mitochondrial translation termination pathway
REACT_267677
Mitochondrial translation elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8VE22
TrEMBL A7M7Q8 Q3TI14
UniProt Splice Variant
Entrez Gene 64656
UniGene
RefSeq NM_001291273 NM_024174 NM_001291270 NM_001291272 XM_006533916
OMIM
CCDS CCDS25227 CCDS70279
HPRD
IMGT
MGI ID MGI:1928138
MGI Symbol Mrps23
EMBL AK014375 AK168051 AL593853 BC019980 CH466556
GenPept AAH19980 BAB29307 BAE40032 EDL15844
RNA Seq Atlas 64656

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca