Homo sapiens Gene: MRPS23
Summary
InnateDB Gene IDBG-60473.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPS23
Gene Name mitochondrial ribosomal protein S23
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181610
Encoded Proteins
mitochondrial ribosomal protein S23
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:57834781-57850056
Strand Reverse strand
Band q22
Transcripts
ENST00000313608 ENSP00000320184
ENST00000579380 ENSP00000463481
ENST00000578444 ENSP00000463677
ENST00000579768
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 30 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0031965 nuclear membrane
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL J3QLC1
UniProt Splice Variant
Entrez Gene 51649
UniGene Hs.5836
RefSeq NM_016070
HUGO HGNC:14509
OMIM 611985
CCDS CCDS11598
HPRD 17592
IMGT
EMBL AC015845
GenPept
RNA Seq Atlas 51649