Mus musculus Gene: Tecpr1
Summary
InnateDB Gene IDBG-208049.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tecpr1
Gene Name tectonin beta-propeller repeat containing 1
Synonyms 2210010N04Rik; mKIAA1358
Species Mus musculus
Ensembl Gene ENSMUSG00000066621
Encoded Proteins
tectonin beta-propeller repeat containing 1
tectonin beta-propeller repeat containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
Tecpr1 activity is necessary for efficient autophagic targeting of bacteria and the suppression of Shigella intracellular replication.
InnateDB Annotation from Orthologs
Summary
[Homo sapiens] TECPR1 activity is necessary for efficient autophagic targeting of bacteria and the suppression of Shigella intracellular replication. (Demonstrated in murine model)
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000205356:
This gene encodes a tethering factor involved in autophagy. The encoded protein is found at autolysosomes, and is involved in targeting protein aggregates, damaged mitochondria, and bacterial pathogens for autophagy [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:144194442-144223615
Strand Reverse strand
Band G2
Transcripts
ENSMUST00000085701 ENSMUSP00000082844
ENSMUST00000153103
ENSMUST00000125672
ENSMUST00000140524
ENSMUST00000151479
ENSMUST00000147992
ENSMUST00000130962 ENSMUSP00000118484
ENSMUST00000153751
ENSMUST00000137149
ENSMUST00000156129
ENSMUST00000136018
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032266 phosphatidylinositol-3-phosphate binding
Biological Process
GO:0000046 autophagic vacuole fusion
GO:0006914 autophagy
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0000421 autophagic vacuole membrane
GO:0005765 lysosomal membrane
GO:0016021 integral component of membrane
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.239412 Mm.458463
RefSeq NM_027410 XM_006504864
OMIM
CCDS CCDS39377
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas