Version 5.4
Mus musculus Gene: Coil
Summary
InnateDB Gene IDBG-208100.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Coil
Gene Name coilin
Synonyms C79982; Cln80; p80; p80-coilin
Species Mus musculus
Ensembl Gene ENSMUSG00000033983
Encoded Proteins
IDBP-208102
coilin
IDBP-265694
coilin
IDBP-536291
coilin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121058:
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:88970252-88991613
Strand Forward strand
Band C
Transcripts
ENSMUST00000036649 ENSMUSP00000047588
ENSMUST00000107898 ENSMUSP00000103530
ENSMUST00000135325 ENSMUSP00000119450
ENSMUST00000140549
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 69 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 69 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0015036 disulfide oxidoreductase activity
GO:0042802 identical protein binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0001674 female germ cell nucleus
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0015030 Cajal body
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000121058
View Gene Order
ENSBTAG00000017275
Not yet available
Cross-References
SwissProt Q5SU73
TrEMBL
UniProt Splice Variant
Entrez Gene 12812
UniGene Mm.268004
RefSeq NM_016706
OMIM
CCDS CCDS36277
HPRD
IMGT
MGI ID MGI:104842
MGI Symbol Coil
EMBL AF208663 AK167167 AL646096 AY047703 AY047704 AY047705 BC031167 CH466556 CU407331
GenPept AAF19644 AAH31167 AAL32280 BAE39306 CAI24263 CAQ52167 EDL15867
RNA Seq Atlas 12812

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca