Version 5.4
Bos taurus Gene: BT.38955
Summary
InnateDB Gene IDBG-629257.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.38955
Gene Name coilin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017275
Encoded Proteins
IDBP-680654
coilin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121058:
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:7988038-8010218
Strand Reverse strand
Band
Transcripts
ENSBTAT00000022956 ENSBTAP00000022956
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 68 interaction(s) predicted by orthology.
Predicted by orthology
Total 68 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0015036 disulfide oxidoreductase activity
GO:0042802 identical protein binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0001674 female germ cell nucleus
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0015030 Cajal body
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000121058
View Gene Order
ENSMUSG00000033983
View Gene Order
Cross-References
SwissProt
TrEMBL F1MEL4
UniProt Splice Variant
Entrez Gene 507580
UniGene Bt.38955
RefSeq NM_001038512
HUGO HGNC:2184
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048263 DAAA02048264 DAAA02048265
GenPept
RNA Seq Atlas 507580

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca