InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp5j2

Summary

InnateDB Gene

IDBG-208603.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp5j2

Gene Name

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2

Synonyms

1110019H14Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000038690

Encoded Proteins

IDBP-208605

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2

IDBP-539642

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2

IDBP-725063

IDBP-540378

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000241468:
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. This gene has multiple pseudogenes. Naturally occurring read-through transcription also exists between this gene and the downstream pentatricopeptide repeat domain 1 (PTCD1) gene. [provided by RefSeq, Nov 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:145183698-145192062

Strand

Reverse strand

Band

Transcripts

ENSMUST00000037056	ENSMUSP00000039726
ENSMUST00000161741	ENSMUSP00000125504
ENSMUST00000162360	ENSMUSP00000138039
ENSMUST00000161845	ENSMUSP00000123904

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016887	ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006754	ATP biosynthetic process
GO:0015992	proton transport

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005753	mitochondrial proton-transporting ATP synthase complex
GO:0016021	integral component of membrane
GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
GO:0070062	extracellular vesicular exosome